Processes and Methods (incl. Screening)

A family of 16-electron binary Ni(0)-stilbene complexes Ni(^Rstb)₃ as a new class of air-stable Ni(0) (pre)catalysts was developed.

A precise and genetically encoded inhibitor for cell-type selective, inducible and reversible inhibition of protein synthesis

Prof. Klaus-Richard Pörschke and co-workers at the MPI for Coal Research developed a novel cyclic process for the quantitative extraction of cesium with 100% selectivity from any given aqueous or acidic solution, irrespective of the other components.

The cellular identity of mature cells that are confined in a specialized genetic expression profile can be overcome by introducing just a few genes that encode for so-called reprogramming factors [1]. By means of this intervention, also known as reprogramming, the cells then become pluripotent and represent induced pluripotent stem cells (iPS cells) [1]. Nowadays, numerous new cell culture models have been established based on reprogramming protocols that yield iPS cells. Such cell culture models ...

An innovative high throughput screening method for measurement of RNA- and DNA-polymerase activity at room temperature, based on time-resolved FRET.

We offer a new family of cationic ligands, namely N-alkyl/aryl pyridiniophosphines. The ligands can be synthesized through a short, scalable, and highly modular route.

Evaluation of their electronic properties evidenced weak σ-donor and quite strong π-acceptor character when used as ancillary ligands.

Extremely sensitive, reliable and fast novel KDAC assay, which can be performed in a continuous format. This novel KDAC assay is based on Firefly luciferase harboring an acetylation on an essential active site lysine, incorporated by genetic code expansion. We furthermore offer a bacterial selection system for KDACs, which uses a reporter enzyme inactivated by lysine modifications at an essential active site residue, thereby linking deacetylase activity to a selectable output.

Scientists in the group of Atmospheric Chemistry at the Max Planck Institute for Chemistry in Mainz have developed a novel thiosulfate based ozone scrubber to ensure accurate measurements of trace analytes. It is known from the literature that commercial potassium iodide (KI) containing ozone scrubbers can cause errors in the measurement of carbonyl compounds such as aldehydes and ketones due to byproducts formed from the oxidation of KI. Commercial ozone scrubbers based on sodium thiosulfate ...

This invention relates to means and methods for conjugating/attaching target molecules such as proteins to a label and/or carrier.

SUMOvera enables versatile purification strategies for broad applications in eukaryotic hosts.

We offer the new composite nanomaterial for sodium ion battery cathodes. These carbon-coated nanosized Na₃V₂(PO₄)₃ particles embedded in a highly effective mixed conducting porous carbon matrix can be easily prepared by means of facile soft-chemistry based preparation method with a post heat treatment procedure. The resulting cathodes can be charged and discharged in 6 s with high current density of 22 A/g, deliver the specific capacity of 44 mAh/g and ...