Optimised Flow-Through-Cell for Online-Microscopy
maximum measurable crystal size has to be much lower than the maximum size determined by the given construction.
The invention covers an improved flow-through-cell for online microscopy. The flow channel was optimised regarding the flow regime and velocities to prevent sedimentation. On the one hand, the inlet and outlet have a round shape facilitating implementation in commonly utilized plant setups and tubings. The measuring portion of the flow channel, on the other hand, is constructed as an oblong hole (s. Fig. 1). This shape – broadened and less in height – ensures the monitoring of individual crystals when passing the windows. To suppress wake space, turbulences and sedimentation, diffusor portions connect the measuring portion with the inlet and outlet, respectively. In the diffusor portion the height and width of the flow are adjusted gradually (s. Fig. 2).
Furthermore, the temperature of the cell can be controlled to prevent crystallisation at the inner surfaces and dissolution, which alters the measurement result. For this purpose, the flow channel is surrounded by a tempered fluid that is pumped from an external heat exchanger. The large surface – more or less the whole channel is covert – allows a precise control of the temperature of the suspension.
- optimised flow in the cell prevents sedimentation
- controlled temperature prevents crystallisation and dissolution
- direct integration to processes via bypass
DE patent applications filed in March 2018.
- Ref.-No.: 01402-5292-BC (286.5 KiB)
Dr. Bernd Ctortecka, M. Phil.
Phone: +49 89 / 29 09 19-20